In this issue you will find all that is new and important about both antibody and T cell mediated rejection of the kidney: two great reviews and several important studies at both histological and molecular levels. Additional papers on experimental data for Il-21 and Il-33, as well as a careful look at microRNA and a novel assay to identify sensation, complement the broad update that this issue of the journal provides. Perfusion systems continue to evolve and there are useful data on COVID vaccine effectiveness tat make clear the value of vaccination for Omicron. There are many more fascinating papers that you cannot afford to miss.
A must read paper about the treatment of early-stage HCC. The risk factors for tumor-related death and the comparison of the results of liver resection and liver transplantation HCC are reported by Di Sandro et al.
ABO-incompatible transplantation has improved accessibility of kidney, heart, and liver transplantation. Pancreatic islet transplantation continues to be ABO-matched, yet ABH antigen expression within isolated human islets or novel human embryonic stem cell (hESC)-derived islets remain uncharacterized. We evaluated ABH glycans within human pancreata, isolated islets, hESC-derived pancreatic progenitors, and the ensuing in vivo mature islets following kidney subcapsular transplantation in rats. Analyses include fluorescence immunohistochemistry and single-cell analysis using flow cytometry.
Atherosclerosis of the aortoiliac vessels can adversely affect kidney perfusion after kidney transplantation. Atherosclerosis severity can be determined using the calcium score (CaScore). Potential problems with posttransplantation kidney perfusion can be determined using the intrarenal resistance index (RI). This study investigated the association between aortoiliac CaScore and RI in kidney transplant recipients.
Last Chance to Submit an LOI for the TTS Research Grants
TTS will provide funding to three individual investigators to support their research in transplantation. The spectrum of studies includes basic, clinical/epidemiological and translational. This individual should have spent five years or less performing research in transplantation (and/or immunology relating to transplant) since obtaining their last doctoral degree (PhD, MD, PharmD, or equivalent). One of these research grants will be preferentially designated to TTS members from a low- or middle-income country. Please send application materials and any questions to jennifer.groverman@tts.org.
Registration: Presenters must be registered and have paid their registration fee by July 24, 2023; otherwise, the abstract will be removed from the program.
ONLY accepted abstracts by a presenter registered to attend the Congress will be published in an online supplement of the Transplantation Journal.
It is the submitter’s responsibility to ensure that all co-authors approve of the abstract’s submission, publication, and potential presentation.