Transplantation sciences have uniquely advanced the clinical art over the last 70 years. Federal funding has always been critical. Since November 2024, the NIH has inaugurated a transplant specific study section that will play a critical role in shaping the future of transplantation research. A special feature in this issue of the journal authored by the inaugural chair, presents an in-depth assessment of this committee’s role and perspective.
Tailoring and optimizing immunosuppression continue to be at the center of any transplant provider. While CNIs represent the mainstay of immunosuppression, side-effects are broadly recognized. Maintenance immunosuppression avoiding CNIs has the advantage of evading some of those side-effects. Belatacept-based regimens, however, have also indicated a higher risk of acute rejections. A review article by key opinion leaders in this issue of the journal, presents data on an optimized conversion to Belatacept.
Novel preservation techniques show great potential with promise to assess, select, preserve and potentially improve organ function. Two experimental studies provide details: Innovative methods are applied to discarded human hearts focusing on incorporating mitochondrial redox state, left ventricular (LV) function, and inflammatory biomarkers into normothermic machine perfusion (NMP) protocols. An additional experimental study in kidneys applied a multi-omics approach to delineate the consequences of preservation and prolonged ischemia.
The diagnosis of Chronic Antibody mediated rejection continues to be a clinical challenge. Peritubular Capillary multilayering is a key diagnostic feature, nevertheless this lesion has not been well defined while variable diagnostic thresholds and criteria have been used. A single center, prospective cohort study provides a detailed analysis and presents peritubular capillary multilayering as a superior histological marker of Chronic Antibody mediated Rejection with high sensitivity.
Enjoy this February issue of the journal with many more highlights.
Stefan G. Tullius, MD, PhD
Editor-in-Chief, Transplantation Journals
📅 Submission deadline: March 19, 2026 — 23:59 (EST)
In 2026, three Officer positions will be vacated and 5 of the 14 Councilors-at-large representing the Regions will be changing. The elections will take place in early 2026 and those elected will assume their new roles starting at the 2026 TTS Congress in Sydney.







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