JUST RELEASED - Transplantation Direct - March 2025 Issue
The March 2025 issue of Transplantation Direct covers many topics in transplantation. Starting with kidney transplantation, we feature articles on the pitfalls of transcription-based diagnostics to determined rejection in transplant biopsies, on transplanting kidneys from donors on renal replacement therapy, and on using plasma exchange and rituximab therapy to prevent FSGS recurrence post-transplantation. Several areas are explored in liver transplantation, including treatment protocols for post-transplant peri-hilar cholangiocarcinoma, use of serum ammonia measurements to assess acute liver failure in pediatric patients, assessment of the need for serial right heart catheterizations in recipients with portopulmonary hypertension, accessibility of transplantation for specific patient groups with alcohol-related liver disease, and thoracoabdominal normothermic regional perfusion outcomes with DCD liver transplants. Intimacy care issues are addressed in lung transplant patients developing penile cancer. Related to our IPITA TTS section partners, we have articles on latest outcomes of allo-islet transplantation in Japan, and on the use of predicted indirectly recognizable T cell epitope (PIRCHE) as a rejection biomarker after kidney-pancreas transplantation. Other biomarkers are also explored for detecting subclinical rejection after multiorgan transplantation. In the area of infectious diseases, there is a report on the latest understanding of COVID-19 vaccination efficacy in pediatric patients. Finally, related to our ISODP section partners, we have an article on using “Donation Advisor" to predict successful donation associated with DCDs.
Neoadjuvant Multiagent Systemic Therapy Approach to Liver Transplantation for Perihilar Cholangiocarcinoma
Nadine Soliman, Ashton A. Connor, Ashish Saharia, Sudha Kodali, Ahmed Elaileh, Khush Patel, Samar Semaan, Tamneet Basra, David W. Victor, III, Caroline J. Simon, Yee Lee Cheah, Mark J. Hobeika, Constance M. Mobley, Mukul Divatia, Sadhna Dhingra, Mary Schwartz, Anaum Maqsood, Kirk Heyne, Maen Abdelrahim, Milind Javle, Jean-Nicolas Vauthey, A. Osama Gaber, R. Mark Ghobrial
Early Registration, Hotel Reservation, and Student Ambassador Program
EARLY REGISTRATION & HOTEL RESERVATIONS NOW OPEN!
Now is the perfect time to plan your participation in this landmark event. Register by May 23, 2025 to take advantage of discounted fees and secure your spot.
The WTC Student Ambassador Program aims to promote transplantation as an exciting and rewarding field of specialization for 3rd and 4th year medical students. By engaging future medical professionals, this program will foster awareness and enthusiasm for organ donation and transplantation while enhancing participation at the WTC 2025 Congress. The application deadline is March 19, 2025.
Recipients receive:
✅ Free Congress Registration
✅ Up to $2,000 Travel Assistance
✅ 4 Nights Stay in Congress Hotel
📅 Apply by March 19, 2025
Tacrolimus-loaded Drug Delivery Systems in Vascularized Composite Allotransplantation: Lessons and Opportunities for Local Immunosuppression
Localized immunosuppression using biomaterial-based drug delivery systems (DDS) offers a promising approach to reducing systemic toxicity while improving graft survival in vascularized composite allotransplantation (VCA). Preclinical models show that TAC-releasing DDS can effectively suppress rejection with minimal side effects, potentially enhancing patient compliance and quality of life.
Unmet Questions About Frailty in Kidney Transplant Candidates
Frailty occurs frequently among patients with advanced chronic kidney disease, especially among women. Assessing frailty in kidney transplant (KT) candidates is crucial for informing them about associated risks. However, there is poor agreement between frailty scales and research on their correlation with transplant outcomes. Being prefrail Frailty is common among kidney transplant (KT) candidates, impacting graft and patient survival even at mild levels. Rather than excluding frail patients, a multimodal prehabilitation approach—including exercise, nutrition, and psychological support—could help improve outcomes, highlighting the need for interventional trials.
Fundamental science and curiosity-driven research are the foundation of modern medicine. We publish groundbreaking basic science publications in areas like Immunology, Cell Therapy, Machine Perfusion, Xenotransplantation, Tissue Typing, Tissue regeneration, Pharmacogenetics, and Translational Science—advancing patient care and preventing rejection. The pioneering discoveries published in Transplantation continue to shape the future of transplantation medicine, driving innovation and progress.
Publishing Basic Science: The basis for improving transplantation medicine!
Carla Baan, Executive editor-Basic Science
Enhance the impact of your basic science research by publishing in Transplantation. As the premier journal in the field, Transplantation provides a platform to share your latest findings in a way that aligns with the current needs, challenges, and exciting opportunities in basic science.
A publication with us makes ameaningful impact!
Reasons to publish with us
Simple submission process
Offers rapid peer review and publication
Global presence
Transplantation is highly cited
Strong social media presence
Do you have research which will advance transplantation? We love to see it!
Clinical Outcomes and Donor-specific Antibody Rebound 5 y After Kidney Transplant Enabled by Imlifidase Desensitization
Imlifidase is an IgG-cleaving endopeptidase conditionally approved in Europe for desensitization of highly sensitized patients before kidney transplantation. We present 5-y outcomes and donor-specific antibody (DSA) levels for clinical trial participants from a single site who received imlifidase for desensitization before incompatible transplantation (NCT02790437).
Sorafenib as Adjuvant Therapy Post–Liver Transplant: A Single-center Experience
Hepatocellular carcinoma (HCC) has a rising incidence and mortality in North America. Liver transplantation (LT) with adjunctive therapies offers excellent outcomes. However, HCC recurrences are associated with high mortality. We investigate whether adjuvant systemic therapy can reduce recurrence, as shown with other malignancies.
CIIRTA 2025 - EXTENDED Abstract Submission Deadline: March 14
XIX Congress of the International Intestinal Rehabilitation and Transplantation Association
One decade after reshaping the field of Intestinal Rehabilitation and Transplantation, we invite you to Gothenburg, the largest small city in Northern Europe, to get up to date with the hot topics of Intestinal Failure and Transplantation.
CIIRTA 2025 will showcase the growing interplay between the various options of intestinal rehabilitation and transplantation and will bring together wolrd's leading surgeons, gastroenterologists and nutrition specialists involved in the care of this challenging patient group. The meeting will blend State of the art lectures by leaders in the field with the cutting edge research taking us into the future. Join us at CIIRTA 2025 (CIIRTA2025.org) and witness the progress in this evolving field.
Important Dates:
Extended Abstract Submission Deadline: March 14, 2025
International Society for Organ Donation Professionals
Free paper and poster sessions will provide the opportunity for donation and transplantation professionals to share their work and experiences. Please note that abstracts previously submitted to, or presented at, other congresses in the past year (e.g. WTC 2025 or TTS 2024) can be resubmitted unless the manuscript has been published in a scientific journal. Abstracts submission for ISODP 2025 will open in March 2025 with information soon to be available, along with information on travel awards. Accepted abstracts that are presented at the ISODP 2025 Congress will be published in an online supplement of the Transplantation Journal.
I am excited to announce the inaugural Women in Transplantation (WIT) seeding grant, designed to address sex and gender inequities among Indigenous Peoples undergoing solid organ transplantation.
Indigenous Peoples, women, and gender-diverse groups face significant systemic barriers to timely transplantation and experience poorer post-transplant outcomes, driven by historical inequities and the impact of social determinants of health. Biological sex and gender roles also shape the progression of chronic disease, access to care, and treatment responses, yet these factors are often overlooked in both research and clinical practice. By prioritising inclusive, culturally safe, and gender-responsive research, this initiative seeks to develop tailored strategies to enhance access to transplantation, improve long-term patient and graft survival, and promote overall well-being. This grant aims to drive sustainable, equitable advancements in transplantation care by fostering meaningful collaboration with key stakeholders.