The August issue of Transplantation Direct has been released! You will find articles on a variety of topics in kidney transplantation, including the cost-effectiveness of valganciclovir prophylaxis vs preemptive therapy, a case report on targeting CD38 in subclinical antibody-mediated rejection in HLA-incompatible kidney transplantation, and IDO+ endothelial cells in glomeruli. In liver transplantation, there are articles on normothermic machine perfusion and its association with mortality and graft failure in the USA, the use of caution in simultaneous liver and kidney transplantation in patients aged 70+, demographic trends in transplant survivors after 3 decades, a case series on rapid development of post–liver transplantation nodular regenerative hyperplasia and portal hypertension after perfusion pump use, as well as a next level article on revolutionary hybrid dual graft using domino and living donors. In pancreas and islet transplantation, an article on video-assisted retroperitoneal debridement for graft pancreatitis. For organ donation, a pharmacoeconomic analysis on the use of machine perfusion to increase the number of expanded criteria deceased donor kidney transplants, and provider and patient perspectives on international travel for organ transplantation. And finally in basic science an article on optimizing DCD liver grafts using stabilized plasm. Please visit the Transplantation Direct website for open access to the full details of these and other articles.