In Collaboration with The Lancet Journal, the American Society of Transplantation, and The European Society of Organ Transplantation

July 17, 2025

Advancing Patient Monitoring, Diagnostics, and Treatment Strategies for Transplant Precision Medicine

Thursday, July 17, 2025 - 8:00 AM (Local time in Montreal)
Local time (Corresponding local time at your current location)
The duration of this presentation is scheduled for 60 minutes.

Overview

Transplant medicine faces substantial challenges, as patients require lifelong immunosuppression to prevent graft rejection. Immunosuppressive regimens to date, while reasonably effective at preventing acute rejection, cause numerous health complications, compromising quality of life and patient survival. A shift towards personalised immunosuppression is needed to improve allograft health, reduce long-term adverse effects, and optimise post- transplant outcomes. This necessity has driven advancements in post-transplant monitoring and diagnostics. Innovative monitoring biomarkers and novel diagnostic modalities have been developed to advance transplant care, with many showing promise for widespread clinical implementation. With advances in artificial intelligence, algorithms have the potential to integrate multidimensional data on the immune system and allograft health, offering a comprehensive view of transplant status. This Series paper highlights the state of post-transplant immunosuppression, monitoring, and diagnostics, emphasising the transformative role of emerging innovations to personalise both allograft and patient care. Their implications could extend to xenotransplantation, further broadening their potential to redefine transplant medicine.

Objectives

  • Understand the current challenges and limitations associated with lifelong immunosuppression in transplant recipients
  • Have an overview of the recent advancements in post-transplant monitoring tools and diagnostic biomarkers, with a focus on their clinical potential for personalizing immunosuppressive regimens
  • Outline future research priorities necessary to validate, standardize, and implement innovative diagnostic strategies in routine transplant clinical practice
  • Outline the emerging role of artificial intelligence in transplant medicine, including how it may be used to integrate complex immunological and clinical data to enhance graft monitoring and decision-making

supporting material

Loupy A, Sablik M, Khush K, Reese P.
Solid Organ Transplantation 2: Advancing patient monitoring, diagnostics, and treatment strategies for transplant precision medicine.
The Lancet. Accepted, In production.
TTS Education Chair
Camille N. Kotton, United States 
Moderator
Bio
TTS Education Co-Chair
Jennifer Li, Australia 
Moderator
Bio
Peter Reese, United States 
Organizer
Bio
Alexandre Loupy, France 
Speaker
Bio
Marta Sablik, France
Speaker
Bio

Use the image below to promote this event (right-click to download)

Social

Contact

Staff Directory
+1-514-874-1717
info@tts.org

Address

The Transplantation Society
International Headquarters
740 Notre-Dame Ouest
Suite 1245
Montréal, QC, H3C 3X6
Canada